Head neck cancer

UCSD ( University of California San Diego ) researchers have identified the molecular mechanism activated by the presence of tetrahydrocannabinol...


Despite the broad activity of checkpoint inhibitors across tumor types, primary or secondary resistance after initial response represents a major...


The European Commission ( EC ) has approved Keytruda , an anti-PD-1 therapy, as monotherapy or in combination with Platinum...


Researchers at Columbia University Medical Center ( CUMC ) have discovered that the fusion of two adjacent genes can...


Immunotherapy has been a major breakthrough in oncology, but little is known about its safety for HIV-positive cancer patients. A...


Researchers at the University of Texas MD Anderson Cancer Center in Houston, have found a link between microbes in the...


In a rigorous study of tumor tissue collected from 125 patients with aggressive brain cancers, researchers at Johns Hopkins say...


Updated data from the ongoing phase 1/2 ECHO-204 trial evaluating the safety and efficacy of Epacadostat, an oral selective IDO1...


Nivolumab ( Opdivo ) maintains function and reduces symptoms in treatment of relapsed metastatic head and neck cancer, according to...


New patient-reported quality-of-life data from an exploratory endpoint in the pivotal phase 3 CheckMate -141 trial evaluating Nivolumab ( Opdivo...


Epacadostat is an oral, potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 ( IDO1 ), a tryptophan-catabolizing enzyme that induces immune...


A treatment harnesses the immune system to shrink tumors in bladder cancer patients that cannot take the most effective chemotherapy. These...


Strategies to help improve the efficacy of the immune system against cancer represent an important innovation, with recent attention having...


The Food and Drug Administration ( FDA ) has approved Keytruda ( Pembrolizumab ), the anti-PD-1 ( programmed death receptor-1...


A new study has provided the first evidence that the mediator complex subunit 15 ( MED15 ) may play a...


The FDA ( Food and Drug Administration ) has granted approval to Lenvima ( Lenvatinib ) to treat patients with...


Immune-suppressing molecules such as PD-L1 can be co-opted by cancer cells to suppress the natural immune response to cancer. Upregulation...


HPV initiated ( HPV+ ) squamous cell carcinoma of oropharynx ( SCCOP ) has a unique epidemiology, biology, and genetic...


Radiotherapy ( RT ) for head and neck cancer ( HNC ) treatment is associated with significant lifelong morbidity. Xerostomia,...


In the treatment of metastatic colorectal cancer, inferior overall survival, progression-free survival, and objective response rates have been shown in...