Growth factors

In MONARCH 2 ( M2 ), Abemaciclib ( Verzenios ), an oral selective cyclin dependent kinase 4 & 6 inhibitor,...


Abemaciclib ( Verzenio ) in combination with standard adjuvant endocrine therapy has met the primary endpoint of invasive disease-free...


A subset of patients treated with immune checkpoint inhibitors experience an accelerated tumor growth rate ( TGR ) in comparison...


The FDA ( U.S. Food and Drug Administration ) has warned that Ibrance ( Palbociclib ), Kisqali ( Ribociclib ),...


Abemaciclib ( Verzenios ) is an oral, selective cyclin-dependent kinase 4 & 6 inhibitor, approved for hormone receptor-positive ( HR+...


Epidermal growth factor receptor inhibitors ( EGFRi ), EGFR tyrosine kinase inhibitors ( TKI ) and anti‐EGFR antibodies commonly develop...


In the REACH-2 trial, Ramucirumab ( Cyramza ) has shown a statistically significant benefit in the primary endpoint of overall...


For patients with prostate cancer, treating the disease with androgen deprivation therapy ( ADT ) is linked to a...


Anthracycline-induced cardiotoxicity was first reported in early 1970s. Since then, there has been increasing recognition of its association with poor...


Data from the pivotal phase 3 LATITUDE clinical trial showed Abiraterone acetate ( Zytiga ) plus Prednisone, in combination with...


Fungal infections that are resistant to treatment are an emerging public health problem, but everyone has a role in preventing...


In non-small cell lung cancer ( NSCLC ) that has already formed metastases, the suitable treatment depends, among other factors,...


Compared with traditional chemotherapy, targeted cancer therapy is a novel strategy in which key molecules in signaling pathways involved in...


A new analysis has indicated that higher body weight and taller stature during adolescence increase the risk of developing non-Hodgkin's...


Hypertension is a common diabetes comorbidity that affects the majority of patients, with the prevalence depending on type of diabetes,...


A new study has provided the first evidence that the mediator complex subunit 15 ( MED15 ) may play a...


Eylea ( Aflibercept ) injection has been recommended for approval by the European Committee for Medicinal Products for Human Use (...


IL-6 is one of the most abundant cytokines in the serum and synovial fluid of patients with rheumatoid arthritis (...


The FDA ( Food and Drug Administration ) has accepted for priority review the supplemental biologics license application ( sBLA...


Fibroblast growth factor 23 ( FGF23 ) and Klotho are associated with vascular calcification and cardiovascular disease in dialysis patients....