GVHD disease

The U.S. Food and Drug Administration ( FDA ) has approved Jakafi ( Ruxolitinib ) for the treatment of steroid-refractory...


The European Commission ( EC ) has approved Kymriah ( Tisagenlecleucel, formerly CTL019 ). The approved indications are for the...


The FDA ( U.S. Food and Drug Administration ) has granted accelerated approval to Keytruda ( Pembrolizumab ) for the...


The FDA ( U.S. Food and Drug Administration ) has approved Keytruda ( Pembrolizumab ), the anti-PD-1 ( programmed death...


Relapse is the major cause of failure after allogeneic stem cell transplantation ( Allo-SCT ) for acute myelogenous leukemia (...


Stimulators of the soluble guanylate cyclase ( sGC ) have recently been shown to inhibit transforming growth factor-beta ( TGF-beta...


Acute graft-versus-host disease ( GVHD ) remains a barrier to more widespread application of allogeneic haemopoietic stem-cell transplantation. Vorinostat (...


No plasma biomarkers are associated with the response of acute graft-versus-host disease ( GVHD ) to therapy after allogeneic hematopoietic...


No plasma biomarkers are associated with the response of acute graft-versus-host disease ( GVHD ) to therapy after allogeneic hematopoietic...


T-cell depleted HLA-haploidentical hematopoietic stem cell transplantation ( HSCT ) is a suitable option for patients in need of an...


Genzyme Europe BV has informed Healthcare Professional of six infection-related deaths, reported from a trial ( CALGB10101 ) in which...


Bayer HealthCare and Genzyme, in collaboration with Health Canada, informed of important safety information regarding the use of MabCampath (...


Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a...


Genzyme Europe BV has informed Healthcare Professional of six infection-related deaths, reported from a trial ( CALGB10101 ) in which...


Gastrointestinal graft-versus-host disease is a common and potentially deadly side effect for patients who undergo an allogeneic stem-cell transplant to...


Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly...


Conditioning with total lymphoid irradiation plus antithymocyte serum protects mice against acute graft-versus-host disease ( GVHD ) after hematopoietic-cell transplantation....