Apoptosis

The CHER-LOB randomized phase II study showed that the combination of Lapatinib ( Tyverb ) and Trastuzumab ( Herceptin )...


Results of a phase 2 open-label, single-arm, multicenter trial to evaluate the efficacy and safety of Blinatumomab ( Blincyto )...


IL-6 is one of the most abundant cytokines in the serum and synovial fluid of patients with rheumatoid arthritis (...


Increasing evidences link T helper 17 ( Th17 ) cells with multiple sclerosis ( MS ). In this context, interleukin-22...


Acute myeloid leukaemia ( AML ) is an aggressive and devastating blood cancer. It predominantly affects people over 60 and...


Results from a phase II study, published in the American Society of Hematology journal Blood, showed patients with previously untreated...



Researchers at Sanford-Burnham Medical Research Institute ( Orlando, Florida; United States ) have identified a set of RNA molecules that...


The use of non-invasive imaging to identify ruptured or high-risk coronary atherosclerotic plaques would represent a major clinical advance for...


A phase-I study for patients with chronic lymphocytic leukaemia has shown promising results. Chronic lymphocytic leukaemia ( CLL ) is...


Nonviral gene therapy represents a realistic option for clinical application in cancer treatment. A preclinical study has demonstrated the advantage...


Researchers have developed a novel strategy for treatment of Leber hereditary optic neuropathy ( LHON ) caused by a mutation...


In Canada, Docetaxel ( Taxotere ) is an injectable chemotherapy drug that was first marketed on December 31, 1995. It...


Due to prophylactic colectomy, mortality in patients with familial adenomatous polyposis ( FAP ) has changed, with duodenal cancer currently...


In the past decades, prophylactic colectomy to prevent development of colorectal cancer substantially has improved prognosis in patients with familial...


Disseminated superficial actinic porokeratosis ( DSAP ) is a disease described in 1966 by Chernosky, and represents the most common...


Several new, targeted therapies show promise to expand treatment options for chronic lymphocytic leukemia ( CLL ) and are more...


The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion, recommending the granting of...


Antiandrogens are a class of drugs used in androgen deprivation therapy for the treatment of advanced or metastatic prostate cancer....


A study for the treatment of heart failure after myocardial infarction found that the extract derived from bone marrow cells...