Anthracyclines

Triple-negative breast cancer ( TNBC ) is an aggressive subtype of breast cancer, often resistant to standard of care therapies....


HER2 targeted therapies have substantially improved the prognosis of patients with breast cancer however they can be associated with cardiac...


Anthracycline-induced cardiotoxicity was first reported in early 1970s. Since then, there has been increasing recognition of its association with poor...


Compared with traditional chemotherapy, targeted cancer therapy is a novel strategy in which key molecules in signaling pathways involved in...


PIK3CA mutations are common in breast cancer. The aim of a study was to evaluate the correlation of PIK3CA mutational...


Cancer Drugs Fund ( CDF ) Panel has assessed the application for Eribulin ( Halaven ) to remain in the CDF...


LABC ( Locally advanced breast cancer ) occurs at first presentation in about one-fifth of breast cancer patients worldwide, with...


As predicted by their DNA-damaging mechanism of action, Platinum compounds are expected to be particularly active in tumours deficient of...


Data from a pooled analysis presented today at the 50th Annual Meeting of the American Society of Clinical Oncology (...


Cancer patients who receive chest radiation should be screened for heart disease every 5-10 years, according to the European Association...


The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion recommending a variation to...


The results of a phase III study ( Study 301 ) of Eribulin mesylate ( Halaven ) versus Capecitabine (...


A new pilot study by Researchers at Memorial Sloan-Kettering Cancer Center ( MSKCC ) found that breast cancer patients can...


Neuroendocrine tumors ( NETs ) comprise a heterogeneous family of neoplasms with a wide and complex spectrum of clinical behavior....


A new pilot study by Researchers at Memorial Sloan-Kettering Cancer Center ( MSKCC ) found that breast cancer patients can...


Gene variations may raise the risk that survivors of childhood cancer will suffer congestive heart failure as a complication of...


A large phase III trial in early-stage HER2-positive breast cancer has shown that adding Herceptin ( Trastuzumab ) to chemotherapy...