Ace inhibitors

Paroxetine is one of the selective serotonin reuptake inhibitors ( SSRIs ) used in the treatment of premature ejaculation. However,...


Inhibition of the P2Y12 receptor by an oral P2Y12 inhibitor with loading doses along with cyclooxygenase-1 inhibition by Aspirin Acetylsalicylic...


Epidermal growth factor receptor inhibitors ( EGFRi ), EGFR tyrosine kinase inhibitors ( TKI ) and anti‐EGFR antibodies commonly develop...


Results from a phase 3 study evaluating Tanezumab 2.5 mg or 5 mg in patients with moderate-to-severe osteoarthritis ( OA...



The European Commission has granted marketing authorisation for Lokelma ( formerly ZS-9, sodium Zirconium cyclosilicate ) for the treatment of...


HER2 targeted therapies have substantially improved the prognosis of patients with breast cancer however they can be associated with cardiac...


Data from the TRANSITION study presented at the European Society of Cardiology ( ESC ) Congress in Munich ( Germany...


Results of the global phase III SOLAR-1 trial evaluating the investigational alpha-specific PI3K inhibitor Alpelisib ( BYL719 ) has met...


Anthracycline-induced cardiotoxicity was first reported in early 1970s. Since then, there has been increasing recognition of its association with poor...


The aim of a population-based cohort study was to determine whether the use of angiotensin converting enzyme inhibitors ( ACEIs...


Findings from two phase 3 studies, COAST-V and COAST-W, in adults with ankylosing spondylitis ( AS ), also referred to...


Pain is one of the most important domains affecting health-related quality of life ( HRQoL ) in patients with psoriatic...


Cancer immunotherapy with checkpoint inhibitors ( CPIs ) is associated with frequent immune-related adverse events ( irAEs ) and is...


A new Expert Consensus Decision Pathway issued by the American College of Cardiology ( ACC ) has recommended Empagliflozin (...


Researchers at Columbia University Medical Center ( CUMC ) have discovered that the fusion of two adjacent genes can...


Chromosomal translocations that generate in-frame oncogenic gene fusions are notable examples of the success of targeted cancer therapies. Gene fusions...


The results from the one-year phase 3 CHRONOS study have shown that patients receiving the investigational drug Dupilumab ( Dupixent...


Evolocumab ( Repatha ), a PCSK9 inhibitor, has shown to dramatically lower levels of low-density lipoprotein ( LDL), and also...


The FDA ( U.S. Food and Drug Administration ) has approved Xadago ( Safinamide ) tablets as an add-on treatment...