Autoantibodies

Patients with rheumatoid arthritis ( RA ) and co-existent bronchiectasis ( BRRA ) have a five-fold increased mortality compared to...


Vitamin D is known as a major regulator of calcium levels and bone metabolism. Furthermore, it also influences the immune...


Clopidogrel ( Plavix ) is a platelet aggregation inhibitor indicated for conditions such as myocardial infarction, stroke or established peripheral...


Idiopathic membranous nephropathy is an autoimmune disease. In approximately 70% of patients, it is associated with autoantibodies against the phospholipase...


Eli Lilly has announced that it will discontinue the phase 3 rheumatoid arthritis ( RA ) program for Tabalumab, an...


Eli Lilly has announced today that it will discontinue the phase 3 rheumatoid arthritis program for Tabalumab, an anti-BAFF (...


Systemic lupus erythematosus ( SLE ) is a chronic systemic autoimmune disease with variable clinical presentation. SLE commonly affects the...


Researchers at the National Institutes of Health ( NIH ) have identified a genetic mutation in three unrelated families that...


The drug Rituximab causes considerable kidney injury healing in patients with membranous nephropathy, a common form of kidney disease, according...


Systemic lupus erythematosus ( SLE ) can affect nearly any part of the body, including the joints, skin, kidneys, heart,...


Treatment with Belimumab ( Benlysta ) resulted in a sustained improvement of systemic lupus erythematosus ( SLE or lupus )...


Two clinical trials of Humira ( Adalimumab ), REVEAL and CHAMPION, have demonstrated promising results in psoriasis. Psoriasis is a...


A study on the long-term outcome of children undergoing liver transplants found that chronic hepatitis was common and that it...


In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise...


Researchers have discovered a combination of tests that can more accurately predict who will develop type 1 diabetes. In the...


More than half of 61 children and adolescents infected with chronic hepatitis C achieved a sustained viral response after treatment...


Researchers at the University of Michigan Comprehensive Cancer Center have identified a panel of 22 biomarkers that together provide a...


Long-term use of anti-TNF-alpha agents can lead to the development of autoantibodies. Infliximab ( Remicade ) is a chimeric human-murine monoclonal...