Atherosclerosis

After analyzing 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, researchers...


The phase 3 GAUSS-3 ( Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3 ) trial evaluating Evolocumab...


A study has evaluated the prospective association between circulating 25-hydroxyvitamin D [ 25(OH)D ] and atrial fibrillation risk. 12 303 participants...


Minimal data are available regarding the long-term mortality risk of subclinical atherosclerosis using coronary artery calcium ( CAC ) scoring...


Body circumferences have been proposed as potential anthropometric measures for the assessment of cardiometabolic risk as they are independently associated...


The use of statins may not be associated with lowering risk for Parkinson's disease ( PD ), according to a...


Autonomic dysfunction frequently occurs in the context of Parkinson disease ( PD ) and may precede onset of motor symptoms....


Accurate risk assessment of atherosclerotic cardiovascular disease ( ASCVD ) is essential to effectively balance the risks and benefits of...


New detailed data from the phase 3 YUKAWA-2 study evaluating Evolocumab ( Repatha ), a novel investigational cholesterol-lowering medication, in...


Phase 2b TULIP study results with CETP inhibitor, TA-8995, a drug in the field of dyslipidemia, were published in the...


A study has estimated the frequency of cardiovascular events that occurred after diagnosis in a large Spanish cohort of patients...


Whether menopausal hormone therapy ( MHT ) protects against cardiovascular disease ( CVD ) remains unclear. A randomized, controlled trial, performed...


Resistant hypertension increases the risk of stroke by 35% in women and 20% in elderly Taiwanese patients, according to research...


Secretory phospholipase A2 ( sPLA2 ) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor Varespladib has favorable effects...


Coronary artery calcium ( CAC ), measured by computed tomography ( CT ), has strong predictive value for incident cardiovascular...


Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 ( PCSK9 ). PCSK9 is a...


Homozygous familial hypercholesterolaemia ( HoFH ) is a rare life-threatening condition characterized by markedly elevated circulating levels of low-density lipoprotein...


It is unclear whether high-density lipoprotein ( HDL ) cholesterol concentration plays a causal role in atherosclerosis. A more important...


Of the theoretical estimated prevalence of 1/500 for heterozygous familial hypercholesterolaemia, less than 1% are diagnosed in most countries. Direct...