Apheresis

Positive results from the phase 3 ODYSSEY ESCAPE trial evaluating Alirocumab ( Praluent ) injection in patients with an inherited...


Lomitapide ( Lojuxta [ EU ], Juxtapid [ US ] ) lowers cholesterol through a different pathway, i.e. through the...


Findings from an ongoing phase IIa study to evaluate the safety and efficacy of investigational chimeric antigen receptor T cell...


Ipilimumab ( Yervoy ) is a novel FDA-approved recombinant human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4 and has been...


Ipilimumab ( Yervoy ) is a novel FDA-approved recombinant human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4 ( CTLA-4 )...


Homozygous familial hypercholesterolaemia ( HoFH ) is a rare life-threatening condition characterized by markedly elevated circulating levels of low-density lipoprotein...


Sleeve gastrectomy is a safe and effective fast growing weight loss surgery option. Nevertheless complications are not rare. Five patients who...


IMPROVE-IT ( IMProved Reduction of Outcomes: VYTORIN Efficacy International Trial ), was an international, multi-center, randomised, double-blind active comparator trial...


Data, published in The Lancet, from two phase 3 studies, RUTHERFORD-2 and TESLA with Evolocumab, a novel investigational low-density lipoprotein...


Severe hypertriglyceridemia ( sHTG ) ( plasma triglyceride level greater than 10 mmol/L ) due to lipoprotein lipase ( LPL...


Capillary leak syndrome ( CLS ) has been reported in recipients of Filgrastim, including patients undergoing chemotherapy and a healthy...


Of the theoretical estimated prevalence of 1/500 for heterozygous familial hypercholesterolaemia, less than 1% are diagnosed in most countries. Direct...



The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion, recommending the granting of...


The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion, recommending the granting of...


The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion, recommending the granting of...


Provenge ( Sipuleucel-T ) is an autologous cellular immunotherapy designed to stimulate a patient’s own immune system against cancer. Provenge...


In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise...