Amyotrophic lateral sclerosis

A study by Indiana University researchers has identified 24 compounds, including Caffeine, with the potential to boost an enzyme in...


The neurite outgrowth inhibitor, Nogo-A, has been shown to be overexpressed in skeletal muscle in amyotrophic lateral sclerosis ( ALS...


A study has evaluated the ability of Lithium carbonate and Valproate cotreatment to modify the survival rate and functional score...


A study has assessed the efficacy and safety of Olesoxime, a molecule with neuroprotective properties, in patients with amyotrophic lateral...


The FDA-approved trial, A Phase 1, Open-Label, First-in-Human, Feasibility and Safety Study of Human Spinal Cord-Derived Neural Stem Cell Transplantation...


Researchers have compared the phase II and phase III ( EMPOWER ) studies of Dexpramipexole in amyotrophic lateral sclerosis (...


Amyotrophic lateral sclerosis ( ALS ) is a rapidly progressive, fatal neurodegenerative disorder affecting the nerve cells that control muscle...


The first clinical trial of a drug intended to delay the onset of symptoms of Huntington disease ( HD )...


Lithium has neuroprotective effects in cell and animal models of amyotrophic lateral sclerosis ( ALS ), and a small pilot...


The Committee for Medicinal Products for Human Use ( CHMP ) has recommended the granting of a marketing authorisation for...


Oculomotor apraxia ( OMA ) associated with cerebellar ataxia was first noted by Boder and Sedgwick in patients with ataxia-telangiectasia...


Apparent stem cell transplant success in mice may hold promise for people with amyotrophic lateral sclerosis ( ALS ), or...


The aim of the study was to investigate the therapeutic potential of iPSC- derived neural stem cells ( NSCs )...


A study has identified a previously unrecognized mutation that causes an inherited form of amyotrophic lateral sclerosis ( ALS )....


Researchers at the San Francisco VA Medical Center ( SFVAMC ) have identified the mechanism by which Minocycline ( Minocin...


A team of researchers at the Weizmann Institute of Science, led by Michal Schwartz of the Neurobiology Department, has come...


Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the...


Researchers at the University of Minnesota Medical School have discovered the gene responsible for a type of ataxia, an incurable...


A study in mice suggests that Alzheimer's disease may be triggered when adult neurons try to divide. The study is published...


Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, amyotrophic lateral sclerosis (...