Amyloid precursor protein

Verubecestat is an investigational small molecule inhibitor of the enzyme beta-site amyloid precursor protein cleaving enzyme 1 ( BACE1 )...


Using high-resolution functional MRI ( fMRI ) imaging in patients with Alzheimer's disease and in mouse models of the disease,...


A research team from The University of Nottingham has helped uncover a second rare genetic mutation which strongly increases the...


A study led by Karolinska Institutet has reported for the first time the positive effects of an active vaccine against...


A dysfunction in the lining of blood vessels that is linked to cardiovascular illness also appears to play a role...


A team of researchers, led by Columbia University Medical Center, Boston University School of Medicine and the University of Toronto,...


A study in mice suggests that Alzheimer's disease may be triggered when adult neurons try to divide. The study is published...


The activity of connections among brain cells significantly affects levels of the toxic protein beta-amyloid that is a major cause...


Researchers from the MassGeneral Institute for Neurodegenerative Disorders ( MIND ) in Charlestown have identified a gene variant that may...


Physical activity seems to inhibit Alzheimer's-like brain changes in mice. The research demonstrated that long-term physical activity enhanced the learning ability...


Young drug abusers are up to three times more likely to suffer brain damage than those who don't use drugs. The...