Alendronate

Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. The monoclonal antibody Romosozumab binds to sclerostin and increases bone formation.In a...


Long-term complications of cystic fibrosis include osteoporosis and fragility fractures, but few data are available about effective treatment strategies, especially...


The results from a phase II trial for Odanacatib, a cathepsin K ( cat-K ) inhibitor in development for the...


Two clinical studies were conducted to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and potential immunogenicity of single and multiple escalating...


A widely prescribed class of drugs is highly effective in reducing common bone fractures in people with osteoporosis, but an...


Researchers found patients with glucocorticoid-induced osteoporosis who were treated with Teriparatide ( Forteo, Forsteo ) for 36 months had a...


Patients who take glucocorticoid drugs ( such as Prednisolone or Prednisone ) to treat a variety of inflammatory/immune-mediated diseases (...


Denosumab ( Prolia ) is a monoclonal antibody against receptor activator of nuclear factor-kappa B ligand ( RANKL ).The following...


Osteoporosis is a growing concern among breast tumor survivors, because certain cancer drugs can cause bone loss.A new study has...


Alendronate ( Fosamax ), a medication used to prevent fractures in women with osteoporosis, may be associated with an increased...


Osteoporosis is a growing concern among breast tumor survivors, because certain cancer drugs can cause bone loss.A new study has...


Most of the cases of osteonecrosis of the jaw are seen in oncology patients that, besides intravenous bisphosphonates, have received...


There is a well-known risk of deterioration in renal function with intravenous bisphosphonates administered at a rapid infusion rate. ADRAC...


Twice-yearly subcutaneous injections of Denosumab ( 60 mg; Prolia ) increased bone mineral density ( BMD ) in the lumbar...


Researchers at the Stanford University School of Medicine have found that a new osteoporosis drug, called Teriparatide ( Forteo ),...


The National Institute for Clinical Excellence ( NICE ) has issued guidance to the NHS in England and Wales on...


Bisphosphonates are drugs commonly used to prevent and treat osteoporosis in post-menopausal women. They are widely used in the management...