Advanced prostate cancer

The FDA ( Food and Drug Administration ) has granted full approval for Tagrisso ( Osimertinib ) 80mg once-daily tablets,...


STAMPEDE is a multigroup, multistage platform trial protocol investigating the efficacy of additional therapy at the time of inception of...


Prostate cancer growth and progression may be linked to neurogenesis and to medical anti- Parkinson treatment, but results are inconclusive....


Recent guidelines recommend against routine screening for prostate cancer, partly because of the risks associated with overtreatment of clinically indolent...


The European Commission ( EC ) has approved Keytruda ( Pembrolizumab ), the anti-PD-1 therapy, at a dose of 2...


The Chemotherapy Clinical Reference Group ( CRG ) has reviewed drugs and drug indications for inclusion on the National cancer...


Longer term ( 18 month ) survival data from CheckMate -057, an open-label, randomized phase 3 study evaluating Nivolumab [...


A new study has provided the first evidence that the mediator complex subunit 15 ( MED15 ) may play a...


The FDA ( Food and Drug Administration ) has approved a new second-generation lung cancer treatment that can help many...


The ASCO Task Force has applied the Framework to four clinical scenarios in which multiple trials have compared new treatment...


Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease ( COPD ), diabetes mellitus, or congestive heart...


Eli Lilly has announced that the REVEL trial, a global phase III study of Ramucirumab in combination with chemotherapy in...


Results from the phase III study of Triptorelin pamoate 11.25 mg ( Decapeptyl 3 months ) administered subcutaneously in patients...


Denosumab ( Prolia ) is a human monoclonal antibody ( IgG2 ) that targets and binds with high affinity and...


According to early results from a randomized controlled clinical trial, men with hormone-sensitive metastatic prostate cancer who received the chemotherapy...


Xofigo is a radiopharmaceutical ( a medicine containing a radioactive substance ) that contains the active substance Radium-223 dichloride. It...


The endothelin pathway has a role in bone metastases, which are characteristic of advanced prostate cancer. Atrasentan, an endothelin receptor...


Poly(ADP-ribose) polymerase ( PARP ) is implicated in DNA repair and transcription regulation. Niraparib is an oral potent, selective PARP-1...


Prostate cancer aggressiveness may be established when the tumor is formed and not alter with time, according to a study...


In a study that included more than 10,000 men with nonmetastatic prostate cancer, use of androgen deprivation therapy ( ADT...