Acetylcholine

Therapeutic repair of myelin disorders may be limited by the relatively slow rate of human oligodendrocyte differentiation. To identify appropriate pharmacological...


New results from a 684-subject phase 2b clinical trial evaluating RVT-101, as an adjunctive therapy to Donepezil in patients with...


Although Vitamin-E and Memantine ( Ebixa, Namenda ) have been shown to have beneficial effects in moderately severe Alzheimer disease,...


Placebo-controlled trials indicate that Cytisine, a partial agonist that binds the nicotinic acetylcholine receptor and is used for smoking cessation,...


A variety of pharmacologic agents are available for the treatment of neurogenic bladder ( NGB ) as part of a...


Memantine ( Ebixa, Namenda ) has been used off-label to treat frontotemporal lobar degeneration ( FTD ). A previous 26-week...


The European Commission granted marketing authorization for Brintellix ( Vortioxetine ) for the treatment of adults with major depressive episodes....


Aclidinium bromide ( Eklira, Bretaris ) has been approved since October 2012 for widening the narrowed airways of adults with...


The investigational compound, Lu AE58054 is a selective 5HT6 receptor antagonist with a different proposed mechanism of action than currently...


The Committee for Medicinal Products for Human Use ( CHMP ) has adopted a positive opinion, recommending the granting of...


Numerous studies have shown that inflammation has a relevant role in the pathogenesis of atherosclerosis as well as of acute...


A new type of treatment significantly reduces the severity of muscle weakness in myasthenia gravis, giving hope for a new...


A study looked at the effects of taking a medication with anticholinergic properties on the annual change in thinking abilities...


Researchers at the New York University School of Medicine provide some of the most compelling evidence yet that long-term exposure...


Nerve signals relayed directly to the pancreas after eating a meal play a critical role in normal blood glucose control. Therefore,...


A study, published in the Clinical Cancer Research, has showed that Botox may have a new use as an...


Researchers at Rhode Island Hospital and Brown Medical School have discovered that insulin and its receptors drop significantly in the...


In a study of people with mild cognitive impairment ( MCI ), those who took the drug Donepezil were...


The mechanism of anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been...